Uploaded image for project: 'UGENE'
  1. UGENE
  2. UGENE-6299

ClustalW erroneously detects alignment alphabet as "Extended amino acid"

    XMLWordPrintable

    Details

    • Type: Bug
    • Status: Closed
    • Priority: Major
    • Resolution: Fixed
    • Affects Version/s: 1.31.1
    • Fix Version/s: 50
    • Component/s: Basic-MSA
    • Labels:
    • Sprint:
      DEV-47-1, DEV-47-2, DEV-47-3, DEV-47-4, DEV-47-5, DEV-47-RELEASE, DEV-48-1, DEV-48-2, DEV-48-3, DEV-48-4, DEV-48-5, DEV-48-RELEASE, DEV-49-1, DEV-49-2, DEV-49-3, DEV-49-4, DEV-49-5, DEV-49-RELEASE, DEV-50-1, DEV-50-2
    • Affect Type:
      Userdefined

      Description

      Scenario:

      1. Open the WD.
      2. Create the following workflow: "Read Alignment" > "Align with ClustalW" > "Write Alignment".
      3. Select "Read Alignment" and input file "sequenceAll_2lineformat.fasta" (the file can be found on the file server in the users dataset folder).
      4. Run the workflow.
        Current result: after reading of the data from the file (this takes about a minute) the workflow finishes. There is the following status on the WD dashboard:
        The workflow task is in progress. There are problems...
        

        There are the following error messages in the UGENE log:

        [ERROR] Unsupported alphabet: Extended amino acid
        [ERROR] Nothing to write
        

        Note that the alignment is quite big and an error notification appears on an attempt to open it in the Alignment Editor.
        However, the "sequenceAll_2lineformat.fasta" file does not contain sequences with "Extended amino acid" alphabet. Each sequence contains only characters from:

        ABCDEFGHIKLMNPQRSTVWXYZ*-
        

        Thus, the error description is incorrect.
        Expected result: ClustalW should either finish successfully or return a more meaningful and correct error.

        Attachments

          Issue Links

            Activity

              People

              Assignee:
              yalgaer Yuliya Algaer
              Reporter:
              oigl Olga Golosova
              Assigned Tester:
              Svetlana Samoilenko
              Watchers:
              1 Start watching this issue

                Dates

                Created:
                Updated:
                Resolved: